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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T9911 | Tocilizumab | Interleukin | |
Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor | |||
T64337 | PF-04745637 | PF4745637,PF 4745637,PF 04745637,PF-4745637 | TRP/TRPV Channel |
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1]. | |||
T6850 | GSK2292767 | PI3K | |
GSK2292767 is a potent and selective PI3Kδ inhibitor. | |||
T0777 | Tilmicosin | LY-177370,EL-870 | Antibacterial , Antibiotic |
Tilmicosin (EL-870) is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia haemolytica. | |||
T15431 | Nemiralisib | GSK2269557 (free base),GSK2269557 | PI3K |
Nemiralisib(GSK-2269557 free base) is an orally available, potent and specific PI3Kδ inhibitor with a pKi of 9.9.Nemiralisib is used for the treatment of respiratory diseases including chronic obstructive pulmonary disea... | |||
T7392 | Revefenacin | TD-4208,GSK1160724 | AChR |
Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease. | |||
T27271 | Enzaplatovir | BTAC585,BTA 585,BTA585,BTA-C585,BTA-585 | RSV |
Enzaplatovir (BTA-585) is an orally available fusion inhibitor with antiviral activity for the study of respiratory syncytial virus infections and coronavirus disease (COVID-19) infections. | |||
T22439 | Tilmicosin phosphate | Antibacterial , Antibiotic | |
Tilmicosin phosphate, a macrolide antibiotic, is used to treat cattle for pathogens that cause Bovine Respiratory Disease. | |||
T60091 | Sodium iodide | Others | |
Sodium iodide is an orally available and radioactive compound for the prevention of respiratory disease in pre-weaned dairy cows. | |||
T2191 | Tacrine hydrochloride (hydrate) | Tacrine,Tacrine hydrochloride hydrate,Tetrahydroaminacrine,Tetrahydroaminoacridine | AChR , AChE |
Tacrine hydrochloride hydrate (Tetrahydroaminacrine) is a cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and i... | |||
T60522 | Letosteine | Viscotiol | Others |
Letosteine (Viscotiol) is an orally active, effective, and safe expectorant that can be used in the study of acute or chronic respiratory diseases, for example, bronchopulmonary disease. Letosteine dissolves bronchial mu... | |||
T72918 | JNJ-49095397 | RV568 | Antiviral , p38 MAPK |
JNJ-49095397 (RV568) is a selective p38 MAPK-α and p38 MAPK--γ kinase inhibitor with anti-inflammatory activity and potential antiviral activity for chronic obstructive pulmonary disease (COPD), cystic fibrosis, and resp... | |||
T0454 | Florfenicol | Nuflor,Aquafen | Others |
Florfenicol (Aquafen) is a fluorinated synthetic analog of thiamphenicol. In the United States, florfenicol is currently used to treat bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica... | |||
T0056 | Oxeladin citrate | Others | |
Oxeladin citrate is a highly potent and effective cough suppressant, which can treat all types of cough of various etiologies. It is not related to opium or its derivatives, so treatment with oxeladin is no risk of add... | |||
T0454L | Florfenicol | SCH-25298,(-)-Florfenicol | Antibacterial , Antibiotic |
Florfenicol (SCH-25298), a fluorinated synthetic analog of thiamphenicol, is currently indicated for the therapy of bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica, Haemophilus somnu... | |||
T68297 | Dilmapimod tosylate | ||
Dilmapimod tosylate is a potent p38 mitogen-activated protein kinase (MAPK) inhibitor. It was investigated for its anti-inflammatory effect in non-head injury trauma patients at risk for developing acute respiratory dist... | |||
T79809 | ROCK-IN-8 | ROCK | |
ROCK-IN-8 (Example 4), a ROCK inhibitor, exhibits anti-inflammatory properties and is suitable for respiratory and gastro-intestinal disease research, demonstrating an IC50 value below 100 nM [1]. | |||
T73816 | Fusafungine | ||
Fusafungine, known commercially as Bioparox, Fusaloyos, and Locabiotal, serves as a potent antibiotic and anti-inflammatory agent effective in oral administration. It shows promise for research related to upper respirato... | |||
T78691 | PI3Kδ-IN-12 | PI3K | |
PI3Kδ-IN-12 (compound 13), a PI3Kδ inhibitor with a pIC50 of 5.8, exhibits differential binding affinities with pKi values of 8.0 for PI3Kδ, 6.5 for PI3Kγ, 6.4 for PI3Kβ, and 6.7 for PI3Kα. This compound is utilized in r... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN1416 | Ayanin | IL Receptor , P450 , PARP , PDE | |
Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma.The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 productio... | |||
TC0039 | Vasicinone | Others | |
Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiprolifer... | |||
T4960 | VASICINE | Anti-infection , AChR | |
Vasicine is oxytocic and abortifacient agents.Vasicine, a potential natural cholinesterase inhibitor, has been in development for treatment of Alzheimer's disease. Vasicine can regulate the inflammatory reaction, have gr... | |||
T5623 | Bisphenol A | Others , Endogenous Metabolite | |
Bisphenol A is an endogenous metabolic compound of phenols and is widely used in the production of epoxy resins and polycarbonate plastics. It is reproductive, developmental and systemic toxicant and is often classified ... | |||
TN3048 | 4-Methoxycinnamaldehyde | p-Methoxycinnamaldehyde | RSV |
4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde) is an active ingredient of Agastache rugosa.4-Methoxycinnamaldehyde has cytoprotective activity against respiratory syncytial virus (RSV) in human laryngeal carcinoma cel... | |||
T67302 | 2,3-Pentanedione | Acetylpropionyl | Others |
2,3-Pentanedione is a food additive that also occurs naturally as a fermentation product in beer, wine and yogurt and is released during the roasting of coffee beans. Inhalation of 2,3-Pentanedione is thought to be the c... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-03851 | BPIFB1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
BPIFB1, also known as LPLUNC1, belongs to the BPI/LBP/Plunc superfamily, plunc family. BPIFB1 may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. BPIFB1 is express... | |||
TMPK-00705 | MASP2 Protein, Human, Recombinant (His) | Human | E. coli |
The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As... | |||
TMPH-00208 | Serotype 3 fimbrial subunit Protein, Bordetella pertussis, Recombinant (His) | Bordetella pertussis | E. coli |
Bordetella pertussis is the causative agent of whooping cough. An essential step in the disease process is the attachment of the bacteria to the ciliated epithelium of the respiratory tract, enabling the organism to resi... | |||
TMPJ-01425 | SARS-CoV-2 NSP1 Protein (His) | SARS-CoV-2 | E. coli |
The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped, positive-stranded RNA viruses that can cause a severe respiratory disease. Its genome consists of a ∼30 kb linear, non-segmented, capped, po... | |||
TMPJ-00704 | SCO1 Protein, Human, Recombinant (GST) | Human | E. coli |
Protein SCO1 Homolog, Mitochondrial (SCO1) is a member of the SCO1/2 family. SCO1 has a homodimer structure. SCO1 is located in mitochondrion and is highly expressed in muscle, heart, and brain. It is characterized by hi... | |||
TMPY-02795 | Eotaxin-2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in imm... |