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Search Results for " respiratory disease "

ターゲット

19

阻害剤

6

天然化合物

6

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T9911 Tocilizumab Interleukin
Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor
T64337 PF-04745637 PF4745637,PF 4745637,PF 04745637,PF-4745637 TRP/TRPV Channel
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].
T6850 GSK2292767 PI3K
GSK2292767 is a potent and selective PI3Kδ inhibitor.
T0777 Tilmicosin LY-177370,EL-870 Antibacterial , Antibiotic
Tilmicosin (EL-870) is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia haemolytica.
T15431 Nemiralisib GSK2269557 (free base),GSK2269557 PI3K
Nemiralisib(GSK-2269557 free base) is an orally available, potent and specific PI3Kδ inhibitor with a pKi of 9.9.Nemiralisib is used for the treatment of respiratory diseases including chronic obstructive pulmonary disea...
T7392 Revefenacin TD-4208,GSK1160724 AChR
Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease.
T27271 Enzaplatovir BTAC585,BTA 585,BTA585,BTA-C585,BTA-585 RSV
Enzaplatovir (BTA-585) is an orally available fusion inhibitor with antiviral activity for the study of respiratory syncytial virus infections and coronavirus disease (COVID-19) infections.
T22439 Tilmicosin phosphate Antibacterial , Antibiotic
Tilmicosin phosphate, a macrolide antibiotic, is used to treat cattle for pathogens that cause Bovine Respiratory Disease.
T60091 Sodium iodide Others
Sodium iodide is an orally available and radioactive compound for the prevention of respiratory disease in pre-weaned dairy cows.
T2191 Tacrine hydrochloride (hydrate) Tacrine,Tacrine hydrochloride hydrate,Tetrahydroaminacrine,Tetrahydroaminoacridine AChR , AChE
Tacrine hydrochloride hydrate (Tetrahydroaminacrine) is a cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and i...
T60522 Letosteine Viscotiol Others
Letosteine (Viscotiol) is an orally active, effective, and safe expectorant that can be used in the study of acute or chronic respiratory diseases, for example, bronchopulmonary disease. Letosteine dissolves bronchial mu...
T72918 JNJ-49095397 RV568 Antiviral , p38 MAPK
JNJ-49095397 (RV568) is a selective p38 MAPK-α and p38 MAPK--γ kinase inhibitor with anti-inflammatory activity and potential antiviral activity for chronic obstructive pulmonary disease (COPD), cystic fibrosis, and resp...
T0454 Florfenicol Nuflor,Aquafen Others
Florfenicol (Aquafen) is a fluorinated synthetic analog of thiamphenicol. In the United States, florfenicol is currently used to treat bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica...
T0056 Oxeladin citrate Others
Oxeladin citrate is a highly potent and effective cough suppressant, which can treat all types of cough of various etiologies. It is not related to opium or its derivatives, so treatment with oxeladin is no risk of add...
T0454L Florfenicol SCH-25298,(-)-Florfenicol Antibacterial , Antibiotic
Florfenicol (SCH-25298), a fluorinated synthetic analog of thiamphenicol, is currently indicated for the therapy of bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica, Haemophilus somnu...
T68297 Dilmapimod tosylate
Dilmapimod tosylate is a potent p38 mitogen-activated protein kinase (MAPK) inhibitor. It was investigated for its anti-inflammatory effect in non-head injury trauma patients at risk for developing acute respiratory dist...
T79809 ROCK-IN-8 ROCK
ROCK-IN-8 (Example 4), a ROCK inhibitor, exhibits anti-inflammatory properties and is suitable for respiratory and gastro-intestinal disease research, demonstrating an IC50 value below 100 nM [1].
T73816 Fusafungine
Fusafungine, known commercially as Bioparox, Fusaloyos, and Locabiotal, serves as a potent antibiotic and anti-inflammatory agent effective in oral administration. It shows promise for research related to upper respirato...
T78691 PI3Kδ-IN-12 PI3K
PI3Kδ-IN-12 (compound 13), a PI3Kδ inhibitor with a pIC50 of 5.8, exhibits differential binding affinities with pKi values of 8.0 for PI3Kδ, 6.5 for PI3Kγ, 6.4 for PI3Kβ, and 6.7 for PI3Kα. This compound is utilized in r...
カタログ番号 製品名 別名 ターゲット
TN1416 Ayanin IL Receptor , P450 , PARP , PDE
Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma.The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 productio...
TC0039 Vasicinone Others
Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiprolifer...
T4960 VASICINE Anti-infection , AChR
Vasicine is oxytocic and abortifacient agents.Vasicine, a potential natural cholinesterase inhibitor, has been in development for treatment of Alzheimer's disease. Vasicine can regulate the inflammatory reaction, have gr...
T5623 Bisphenol A Others , Endogenous Metabolite
Bisphenol A is an endogenous metabolic compound of phenols and is widely used in the production of epoxy resins and polycarbonate plastics. It is reproductive, developmental and systemic toxicant and is often classified ...
TN3048 4-Methoxycinnamaldehyde p-Methoxycinnamaldehyde RSV
4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde) is an active ingredient of Agastache rugosa.4-Methoxycinnamaldehyde has cytoprotective activity against respiratory syncytial virus (RSV) in human laryngeal carcinoma cel...
T67302 2,3-Pentanedione Acetylpropionyl Others
2,3-Pentanedione is a food additive that also occurs naturally as a fermentation product in beer, wine and yogurt and is released during the roasting of coffee beans. Inhalation of 2,3-Pentanedione is thought to be the c...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-03851 BPIFB1 Protein, Human, Recombinant (His) Human HEK293 Cells
BPIFB1, also known as LPLUNC1, belongs to the BPI/LBP/Plunc superfamily, plunc family. BPIFB1 may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. BPIFB1 is express...
TMPK-00705 MASP2 Protein, Human, Recombinant (His) Human E. coli
The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As...
TMPH-00208 Serotype 3 fimbrial subunit Protein, Bordetella pertussis, Recombinant (His) Bordetella pertussis E. coli
Bordetella pertussis is the causative agent of whooping cough. An essential step in the disease process is the attachment of the bacteria to the ciliated epithelium of the respiratory tract, enabling the organism to resi...
TMPJ-01425 SARS-CoV-2 NSP1 Protein (His) SARS-CoV-2 E. coli
The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped, positive-stranded RNA viruses that can cause a severe respiratory disease. Its genome consists of a ∼30 kb linear, non-segmented, capped, po...
TMPJ-00704 SCO1 Protein, Human, Recombinant (GST) Human E. coli
Protein SCO1 Homolog, Mitochondrial (SCO1) is a member of the SCO1/2 family. SCO1 has a homodimer structure. SCO1 is located in mitochondrion and is highly expressed in muscle, heart, and brain. It is characterized by hi...
TMPY-02795 Eotaxin-2 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in imm...